Polyploidization and Cancer Randy Y.C. Poon

ISBN: 9781441961983

Published: May 21st 2010

Hardcover

151 pages


Description

Polyploidization and Cancer  by  Randy Y.C. Poon

Polyploidization and Cancer by Randy Y.C. Poon
May 21st 2010 | Hardcover | PDF, EPUB, FB2, DjVu, talking book, mp3, ZIP | 151 pages | ISBN: 9781441961983 | 3.49 Mb

Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promoteMoreLimiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation.

A growing body of evidence indicates that the surveillance mechanisms that prevent polyploidization are frequently perturbed in cancers. Progress in the past several years has unraveled some of the underlying principles that maintain genome stability. This book brings together leaders of the field to overview subjects relating to polyploidization and cancer.



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